Covid-19 Reinfection May Be More Aggressive Even Without Variants, Study Says

Second Covid-19 contagion causes more intense inflammatory body response and stronger symptoms
Photo: CNN

Asymptomatic people and those with mild or moderate symptoms of Covid-19 are at risk of reinfection by the disease, even if they have not been contaminated by one of the variants of concern, such as the Amazon P1, in addition to strains from the United Kingdom and South Africa .

In these cases, the second contagion causes a more intense inflammatory body response and with stronger symptoms, shows a pre-published study, that is, not yet peer-reviewed, by researchers from the Oswaldo Cruz Foundation (Fiocruz), Federal University of Rio de Janeiro. Janeiro (UFRJ) and Instituto D’Or de Ensino e Pesquisa (Idor).

This study used examples of reinfections that occurred in the state of Rio de Janeiro that showed that patients developed more acute symptoms in relation to the first infection, even though they were not contaminated with some of these variants.

According to Fernando Bozza, one of the researchers responsible for the study that works at Fiocruz and Idor, this risk of reinfection in relation to the new variants is greater, but the focus of the study, which did not address these strains, was the cases of infection by non-variant strains, something new until then.

The data is worrying, as it overturns the idea that reinfection only occurs due to new variants such as P.1, B.1.1.9 (from the United Kingdom) and B.1351 (from South Africa).

According to Bozza, the data further reinforces the need to maintain measures to contain the new coronavirus, such as social isolation, reduced circulation of people, use of masks and hygiene.

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