Mutations may cause new ‘devastating’ outbreaks and render vaccines ineffective, media says – Correio do Brasil

Mutations may cause new ‘devastating’ outbreaks and render vaccines ineffective, media says – Correio do Brasil
Mutations may cause new ‘devastating’ outbreaks and render vaccines ineffective, media says – Correio do Brasil

A number of studies have shown that, while existing vaccines still work against new strains of coronavirus, they may prove to be less effective in fighting infections.

Mutations of covid-19 may cause new ‘devastating’ outbreaks and render vaccines ineffective, media says

Pathogens in covid-19 can transform into a new super-powerful strain that is not susceptible to vaccines and would thus be able to infect the global population again in a “very, very scary” outbreak, with even more capacity to spread, writes tabloid The Sun.

Dr. Tony Lockett, of the Pharmaceutical Science Institute at King’s College London, highlighted the prospect of a devastating new mutation, advising people to strictly follow the rules.

According to a specialist, the effect could be much worse than the first outbreak, since the younger ones could become sicker and the newly cured ones would be reinfected with the new strain.

Lockett explained that some mutations arise when the virus infects people who are unable to defeat it with their own immune system.

– Uncontrolled proliferation causes the virus to replicate more actively and in this way [o surgimento de] mutation is more likely – he said, adding that the most effective way to deal with the threat is to “vaccinate as much as possible”, thereby reducing the rate of transmission, while maintaining confinement until the majority of the population is immunized .

William Hannage, a Harvard professor, explained that it is crucial to stop the spread of new variants before they gain ground, pointing out that the spread of infections stimulates new mutations.

– Currently there is a lot of concern around E484K, a mutation in the spike protein, which is considered to help the virus bypass the immunity (obtained) from the previous infection and is found in some of the variants – he said.

Protection

– Although it appears that vaccines still offer protection, at least against serious illnesses, this [mutação] must be monitored – he stressed.

Scientist Ravi Gupta, professor of microbiology at the University of Cambridge, warned that the mutations are already in the process of becoming immune to existing vaccines.

– For example, the AstraZeneca study showed that [a vacina] did not show a good result against the South African variant – he said, claiming based on evidence that the same mutations “are emerging again”.

Gupta explained that the Brazil and South Africa variants have the specific E484K mutation that really makes it difficult for our bodies to neutralize and prevent the spread of the infection.

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